PEG-PLA hydrogels by stereocomplexation for tissue engineering of cartilage.

نویسندگان

  • C Hiemstra
  • Z Zhong
  • P J Dijkstra
  • J Feijen
چکیده

PEG–PLA hydrogels were prepared by stereocomplexation of poly(lactide) (PLA) blocks of opposite chirality. Gelation occurred upon mixing aqueous solutions of both enantiomers of PEG6500–(PLA)2, PEG12500–(PLA)2 and PEG21800–(PLA)8 block copolymers. Stereocomplexed hydrogels from PEG6500–(PLA)2 polymers were found to be stable up to ~37 8C, while those from PEG12500–(PLA)2 and PEG21800–(PLA)8 block copolymers were stable up to ~50 8C.

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عنوان ژورنال:
  • Journal of controlled release : official journal of the Controlled Release Society

دوره 101 1-3  شماره 

صفحات  -

تاریخ انتشار 2005